Rational Design of Novel Inhibitors of α-Glucosidase: An Application of Quantitative Structure Activity Relationship and Structure-Based Virtual Screening

α-Glucosidase is considered a prime drug target for Diabetes Mellitus and its inhibitors are used to delay carbohydrate digestion for the treatment of diabetes mellitus. With the aim to design α-glucosidase inhibitors with novel chemical scaffolds, three folds ligand and structure based virtual scre...

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Detalles Bibliográficos
Autores principales: Halim, Sobia Ahsan, Jabeen, Sumaira, Khan, Ajmal, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158765/
https://www.ncbi.nlm.nih.gov/pubmed/34069325
http://dx.doi.org/10.3390/ph14050482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158765/
https://www.ncbi.nlm.nih.gov/pubmed/34069325
http://dx.doi.org/10.3390/ph14050482

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