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DDX3X Links NLRP11 to the Regulation of Type I Interferon Responses and NLRP3 Inflammasome Activation

Tight regulation of inflammatory cytokine and interferon (IFN) production in innate immunity is pivotal for optimal control of pathogens and avoidance of immunopathology. The human Nod-like receptor (NLR) NLRP11 has been shown to regulate type I IFN and pro-inflammatory cytokine responses. Here, we...

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Detalles Bibliográficos
Autores principales: Kienes, Ioannis, Bauer, Sarah, Gottschild, Clarissa, Mirza, Nora, Pfannstiel, Jens, Schröder, Martina, Kufer, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158815/
https://www.ncbi.nlm.nih.gov/pubmed/34054816
http://dx.doi.org/10.3389/fimmu.2021.653883