Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer

Breast cancer is a very heterogeneous disease, and ~30% of breast cancer patients succumb to metastasis, highlighting the need to understand the mechanisms of breast cancer progression in order to identify new molecular targets for treatment. Sphingosine kinase 1 (SK1) has been shown to be upregulat...

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Detalles Bibliográficos
Autores principales: Velazquez, Fabiola N., Zhang, Leiqing, Viscardi, Valentina, Trocchia, Carolena, Hannun, Yusuf A., Obeid, Lina M., Snider, Ashley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158862/
https://www.ncbi.nlm.nih.gov/pubmed/34043703
http://dx.doi.org/10.1371/journal.pone.0252311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158862/
https://www.ncbi.nlm.nih.gov/pubmed/34043703
http://dx.doi.org/10.1371/journal.pone.0252311

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