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Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection

Complement activation has been implicated in the pathogenesis of severe SARS-CoV-2 infection. However, it remains to be determined whether increased complement activation is a broad indicator of critical illness (and thus, no different in COVID-19). It is also unclear which pathways are contributing...

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Detalles Bibliográficos
Autores principales: Ma, Lina, Sahu, Sanjaya K., Cano, Marlene, Kuppuswamy, Vasanthan, Bajwa, Jamal, McPhatter, Ja’Nia, Pine, Alexander, Meizlish, Matthew L., Goshua, George, Chang, C-Hong, Zhang, Hanming, Price, Christina, Bahel, Parveen, Rinder, Henry, Lei, Tingting, Day, Aaron, Reynolds, Daniel, Wu, Xiaobo, Schriefer, Rebecca, Rauseo, Adriana M., Goss, Charles W., O’Halloran, Jane A., Presti, Rachel M., Kim, Alfred H., Gelman, Andrew E., Dela Cruz, Charles S., Lee, Alfred I., Mudd, Philip A., Chun, Hyung J., Atkinson, John P., Kulkarni, Hrishikesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158979/
https://www.ncbi.nlm.nih.gov/pubmed/34446527
http://dx.doi.org/10.1126/sciimmunol.abh2259