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Structure-mechanics statistical learning unravels the linkage between local rigidity and global flexibility in nucleic acids

The mechanical properties of nucleic acids underlie biological processes ranging from genome packaging to gene expression, but tracing their molecular origin has been difficult due to the structural and chemical complexity. We posit that concepts from machine learning can help to tackle this long-st...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Tsao, Yang, Haw, Chu, Jhih-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159235/
https://www.ncbi.nlm.nih.gov/pubmed/34122953
http://dx.doi.org/10.1039/d0sc00480d