Ligand-centred redox activation of inert organoiridium anticancer catalysts

Organometallic complexes with novel activation mechanisms are attractive anticancer drug candidates. Here, we show that half-sandwich iodido cyclopentadienyl iridium(iii) azopyridine complexes exhibit potent antiproliferative activity towards cancer cells, in most cases more potent than cisplatin. D...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-Ying, Banerjee, Samya, Hughes, George M., Bridgewater, Hannah E., Song, Ji-Inn, Breeze, Ben G., Clarkson, Guy J., Coverdale, James P. C., Sanchez-Cano, Carlos, Ponte, Fortuna, Sicilia, Emilia, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159363/
https://www.ncbi.nlm.nih.gov/pubmed/34094073
http://dx.doi.org/10.1039/d0sc00897d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159363/
https://www.ncbi.nlm.nih.gov/pubmed/34094073
http://dx.doi.org/10.1039/d0sc00897d

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