Small molecule-mediated co-assembly of amyloid-β oligomers reduces neurotoxicity through promoting non-fibrillar aggregation

Amyloid-β (Aβ) oligomers, particularly low molecular weight (LMW) oligomers, rather than fibrils, contribute very significantly to the onset and progression of Alzheimer's Disease (AD). However, due to the inherent heterogeneity and metastability of oligomers, most of the conventional anti-olig...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Qian, Chengyuan, Yang, Tao, Wang, Yanqing, Luo, Jian, Zhang, Changli, Wang, Xiaohui, Wang, Xiaoyong, Guo, Zijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159368/
https://www.ncbi.nlm.nih.gov/pubmed/34123000
http://dx.doi.org/10.1039/d0sc00392a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159368/
https://www.ncbi.nlm.nih.gov/pubmed/34123000
http://dx.doi.org/10.1039/d0sc00392a

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