Cargando…

Enantio- and diastereoselective conjugate borylation/Mannich cyclization

Strategies to capitalize on enolate intermediates generated from stereoselective conjugate borylation to α,β-unsaturated carbonyl systems are surprisingly rare despite the ubiquity of Michael acceptors, and the potential to generate valuable scaffolds bearing multiple stereocenters. Herein, we repor...

Descripción completa

Detalles Bibliográficos
Autores principales: Larin, Egor M., Loup, Joachim, Polishchuk, Iuliia, Ross, Rachel J., Whyte, Andrew, Lautens, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159378/
https://www.ncbi.nlm.nih.gov/pubmed/34094079
http://dx.doi.org/10.1039/d0sc02421j