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Pyrazolone ligation-mediated versatile sequential bioconjugations

Bioconjugation chemistries are critical tools in biotherapeutics discovery. The past efforts have been exclusively focused on two-segment conjugations. However, emerging research directions, such as polypharmacy biotherapeutics, desire multiple-component bioconjugations where more than two pharmacol...

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Detalles Bibliográficos
Autores principales: Mailig, Melrose, Liu, Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159397/
https://www.ncbi.nlm.nih.gov/pubmed/34123011
http://dx.doi.org/10.1039/d0sc02466j