Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses

The mechanism of amyloid co-aggregation and its nucleation process are not fully understood in spite of extensive studies. Deciphering the interactions between proinflammatory S100A9 protein and Aβ(42) peptide in Alzheimer's disease is fundamental since inflammation plays a central role in the...

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Detalles Bibliográficos
Autores principales: Pansieri, Jonathan, Iashchishyn, Igor A., Fakhouri, Hussein, Ostojić, Lucija, Malisauskas, Mantas, Musteikyte, Greta, Smirnovas, Vytautas, Schneider, Matthias M., Scheidt, Tom, Xu, Catherine K., Meisl, Georg, Knowles, Tuomas P. J., Gazit, Ehud, Antoine, Rodolphe, Morozova-Roche, Ludmilla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159403/
https://www.ncbi.nlm.nih.gov/pubmed/34122996
http://dx.doi.org/10.1039/c9sc05905a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159403/
https://www.ncbi.nlm.nih.gov/pubmed/34122996
http://dx.doi.org/10.1039/c9sc05905a

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