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First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated β-galactosidase

Human senescence-associated β-galactosidase (SA-β-gal), the most widely used biomarker of aging, is a valuable tool for assessing the extent of cell ‘healthy aging’ and potentially predicting the health life span of an individual. Human SA-β-gal is an endogenous lysosomal enzyme expressed from GLB1,...

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Detalles Bibliográficos
Autores principales: Li, Xiaokang, Qiu, Wenjing, Li, Jinwen, Chen, Xi, Hu, Yulu, Gao, Ying, Shi, Donglei, Li, Xinming, Lin, Huiling, Hu, Zelan, Dong, Guoqiang, Sheng, Chunquan, Jiang, Bei, Xia, Conglong, Kim, Chu-Young, Guo, Yuan, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159415/
https://www.ncbi.nlm.nih.gov/pubmed/34123013
http://dx.doi.org/10.1039/d0sc01234c