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N(2)Phos – an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki–Miyaura cross couplings in water

A new biaryl phosphine-containing ligand from an active palladium catalyst for ppm level Suzuki–Miyaura couplings, enabled by an aqueous micellar reaction medium. A wide array of functionalized substrates including aryl/heteroaryl bromides are amenable, as are, notably, chlorides. The catalytic syst...

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Detalles Bibliográficos
Autores principales: Akporji, Nnamdi, Thakore, Ruchita R., Cortes-Clerget, Margery, Andersen, Joel, Landstrom, Evan, Aue, Donald H., Gallou, Fabrice, Lipshutz, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159421/
https://www.ncbi.nlm.nih.gov/pubmed/34122976
http://dx.doi.org/10.1039/d0sc00968g