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A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein

Soluble forms of aggregated tau misfolded protein, generally termed oligomers, are considered to be the most toxic species of the different assembly states that are the pathological components of neurodegenerative disorders. Therefore, a critical biomedical need exists for imaging probes that can id...

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Detalles Bibliográficos
Autores principales: Zhao, Yanyan, Tietz, Ole, Kuan, Wei-Li, Haji-Dheere, Abdul K., Thompson, Stephen, Vallin, Benjamin, Ronchi, Elisabetta, Tóth, Gergely, Klenerman, David, Aigbirhio, Franklin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159431/
https://www.ncbi.nlm.nih.gov/pubmed/34122933
http://dx.doi.org/10.1039/c9sc05620c