Biomimetic nanoscale metal–organic framework harnesses hypoxia for effective cancer radiotherapy and immunotherapy

Tumor hypoxia presents a major impediment to effective cancer therapy with ionizing radiation and immune checkpoint inhibitors. Here we report the design of a biomimetic nanoscale metal–organic-framework (nMOF), Hf-DBP-Fe, with catalase-like activity to decompose elevated levels of H(2)O(2) in hypox...

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Detalles Bibliográficos
Autores principales: Ni, Kaiyuan, Lan, Guangxu, Song, Yang, Hao, Ziyang, Lin, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159451/
https://www.ncbi.nlm.nih.gov/pubmed/34094142
http://dx.doi.org/10.1039/d0sc01949f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159451/
https://www.ncbi.nlm.nih.gov/pubmed/34094142
http://dx.doi.org/10.1039/d0sc01949f

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