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Chemical synthesis and immunological evaluation of new generation multivalent anticancer vaccines based on a Tn antigen analogue

Tumor associated carbohydrate antigens (TACAs), such as the Tn antigen, have emerged as key targets for the development of synthetic anticancer vaccines. However, the induction of potent and functional immune responses has been challenging and, in most cases, unsuccessful. Herein, we report the desi...

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Detalles Bibliográficos
Autores principales: Pifferi, Carlo, Ruiz-de-Angulo, Ane, Goyard, David, Tiertant, Claire, Sacristán, Nagore, Barriales, Diego, Berthet, Nathalie, Anguita, Juan, Renaudet, Olivier, Fernández-Tejada, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159477/
https://www.ncbi.nlm.nih.gov/pubmed/34122907
http://dx.doi.org/10.1039/d0sc00544d