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Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants

The opioid receptor (OPR) family comprises the mu-, delta-, and kappa-opioid, and nociceptin receptors that belong to the superfamily of 7-transmembrane spanning G protein-coupled receptors (GPCRs). The mu-opioid receptor is the main target for clinically used opioid analgesics, and its biology has...

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Detalles Bibliográficos
Autores principales: Piltonen, Marjo, Krokhotin, Andrey, Parisien, Marc, Bérubé, Pierre, Djambazian, Haig, Sladek, Rob, Dokholyan, Nikolay V., Shabalina, Svetlana A., Diatchenko, Luda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159799/
https://www.ncbi.nlm.nih.gov/pubmed/33010019
http://dx.doi.org/10.1007/s10571-020-00971-7