Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway

ABSTRACT: Colorectal cancer stem cells (CSCs) have the potential for self-renewal, proliferation, and differentiation. And LGR5 is a stem cell marker gene of colorectal cancer. Curcumin can suppress oncogenicity of many cancer cells, yet the effect and mechanism of curcumin in LGR5(+) colorectal can...

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Detalles Bibliográficos
Autores principales: Mao, Xiaohong, Zhang, Xin, Zheng, Xiaowei, Chen, Yongwu, Xuan, Zixue, Huang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159825/
https://www.ncbi.nlm.nih.gov/pubmed/33713277
http://dx.doi.org/10.1007/s11418-021-01505-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159825/
https://www.ncbi.nlm.nih.gov/pubmed/33713277
http://dx.doi.org/10.1007/s11418-021-01505-1

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