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A Compendium of Kinetic Modulatory Profiles Identifies Ferroptosis Regulators

Cell death can be executed by regulated apoptotic and non-apoptotic pathways, including the iron-dependent process of ferroptosis. Small molecules are essential tools for studying the regulation of cell death. Using time-lapse imaging, and a library of 1,833 bioactive compounds, we assembled a large...

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Detalles Bibliográficos
Autores principales: Conlon, Megan, Poltorack, Carson D., Forcina, Giovanni C., Armenta, David A., Mallais, Melodie, Perez, Marcos A., Wells, Alex, Kahanu, Alexis, Magtanong, Leslie, Watts, Jennifer L., Pratt, Derek A., Dixon, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159879/
https://www.ncbi.nlm.nih.gov/pubmed/33686292
http://dx.doi.org/10.1038/s41589-021-00751-4