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A Compendium of Kinetic Modulatory Profiles Identifies Ferroptosis Regulators
Cell death can be executed by regulated apoptotic and non-apoptotic pathways, including the iron-dependent process of ferroptosis. Small molecules are essential tools for studying the regulation of cell death. Using time-lapse imaging, and a library of 1,833 bioactive compounds, we assembled a large...
Autores principales: | Conlon, Megan, Poltorack, Carson D., Forcina, Giovanni C., Armenta, David A., Mallais, Melodie, Perez, Marcos A., Wells, Alex, Kahanu, Alexis, Magtanong, Leslie, Watts, Jennifer L., Pratt, Derek A., Dixon, Scott J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159879/ https://www.ncbi.nlm.nih.gov/pubmed/33686292 http://dx.doi.org/10.1038/s41589-021-00751-4 |
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