Cargando…

Modular network mechanism of CCN1-associated resistance to HSV-1-derived oncolytic immunovirotherapies for glioblastomas

Glioblastomas (GBMs) are the most common and lethal primary brain malignancy in adults. Oncolytic virus (OV) immunotherapies selectively kill GBM cells in a manner that elicits antitumor immunity. Cellular communication network factor 1 (CCN1), a protein found in most GBM microenvironments, expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Monie, Dileep D., Correia, Cristina, Zhang, Cheng, Ung, Choong Yong, Vile, Richard G., Li, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159930/
https://www.ncbi.nlm.nih.gov/pubmed/34045642
http://dx.doi.org/10.1038/s41598-021-90718-1