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Extracellular vesicles derived from mesenchymal stem cells containing microRNA-381 protect against spinal cord injury in a rat model via the BRD4/WNT5A axis

AIMS: Non-coding microRNA (miRNA) in extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) may promote neuronal repair after spinal cord injury (SCI). In this paper we report on the effects of MSC-EV-microRNA-381 (miR-381) in a rodent model of SCI. METHODS: In the current study, th...

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Detalles Bibliográficos
Autores principales: Jia, Xufeng, Huang, Guangping, Wang, Shaohua, Long, Miao, Tang, Xiaojun, Feng, Daxiong, Zhou, Qingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160032/
https://www.ncbi.nlm.nih.gov/pubmed/34024119
http://dx.doi.org/10.1302/2046-3758.105.BJR-2020-0020.R1