Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine

IL22 is an important cytokine involved in the intestinal defense mechanisms against microbiome. By using ileum-derived organoids, we show that the expression of anti-microbial peptides (AMPs) and anti-viral peptides (AVPs) can be induced by IL22. In addition, we identified a bacterial and a viral ro...

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Detalles Bibliográficos
Autores principales: Klooster, Jean Paul ten, Bol-Schoenmakers, Marianne, van Summeren, Kitty, van Vliet, Arno L. W., de Haan, Cornelis A. M., van Kuppeveld, Frank J. M., Verkoeijen, Saertje, Pieters, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160143/
https://www.ncbi.nlm.nih.gov/pubmed/34045640
http://dx.doi.org/10.1038/s42003-021-02176-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160143/
https://www.ncbi.nlm.nih.gov/pubmed/34045640
http://dx.doi.org/10.1038/s42003-021-02176-0

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