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NUMB suppression by miR-9-5P enhances CD44(+) prostate cancer stem cell growth and metastasis

Experimental and clinical studies over the past two decades have provided overwhelming evidence that human cancers, including prostate cancer (PCa), harbor cancer stem cells (CSCs) that sustain tumor growth, drive tumor progression and mediate therapy resistance and tumor relapse. Recent studies hav...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, Cai, Jun, Zhao, Lei, Zhang, Dejun, Xu, Guojie, Hu, Jianli, Zhang, Tao, Jin, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160147/
https://www.ncbi.nlm.nih.gov/pubmed/34045601
http://dx.doi.org/10.1038/s41598-021-90700-x