Cargando…

NUMB suppression by miR-9-5P enhances CD44(+) prostate cancer stem cell growth and metastasis

Experimental and clinical studies over the past two decades have provided overwhelming evidence that human cancers, including prostate cancer (PCa), harbor cancer stem cells (CSCs) that sustain tumor growth, drive tumor progression and mediate therapy resistance and tumor relapse. Recent studies hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xuan, Cai, Jun, Zhao, Lei, Zhang, Dejun, Xu, Guojie, Hu, Jianli, Zhang, Tao, Jin, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160147/ https://www.ncbi.nlm.nih.gov/pubmed/34045601 http://dx.doi.org/10.1038/s41598-021-90700-x

Ejemplares similares

Cytotoxicity of curcumin against CD44(±) prostate cancer cells: Roles of miR-383 and miR-708
por: Panahizadeh, Reza, et al.
Publicado: (2023)

Metastasis of prostate carcinoma in the mandible manifesting as numb chin syndrome
por: Aksoy, Secil, et al.
Publicado: (2014)

Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44
por: Liu, Can, et al.
Publicado: (2011)

miR-192-5p suppresses the progression of lung cancer bone metastasis by targeting TRIM44
por: Zou, Peng, et al.
Publicado: (2019)

The Suppression of WRKY44 by GIGANTEA-miR172 Pathway Is Involved in Drought Response of Arabidopsis thaliana
por: Han, Yingying, et al.
Publicado: (2013)

Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
por: Li, Jia, et al.
Publicado: (2015)

Replication Study: The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
por: Yan, Xuefei, et al.
Publicado: (2019)

MiR-6511b-5p suppresses metastasis of pMMR colorectal cancer through methylation of CD44 by directly targeting BRG1
por: Sun, JinMing, et al.
Publicado: (2022)

miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44
por: Sun, Lina, et al.
Publicado: (2019)

MiR-205-5p/GGCT Attenuates Growth and Metastasis of Papillary Thyroid Cancer by Regulating CD44
por: Li, Han-Ning, et al.
Publicado: (2022)

Long non-coding RNA ATB promotes human non-small cell lung cancer proliferation and metastasis by suppressing miR-141-3p
por: Lu, Guojie, et al.
Publicado: (2020)

Correction: The Suppression of WRKY44 by GIGANTEA-miR172 Pathway Is Involved in Drought Response of Arabidopsis thaliana
por: Han, Yingying, et al.
Publicado: (2015)

Progressive lip numbness due to numb chin and cheek syndrome in a patient with prostate cancer
por: Rabadi, Meheroz H.
Publicado: (2020)

Prostate adenocarcinoma mandibular metastasis associated with numb chin syndrome: a case report
por: Kim, Il-Kyu, et al.
Publicado: (2016)

miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling
por: Wang, Zhi-Chao, et al.
Publicado: (2020)

Retraction: miR-5089-5p suppresses castration-resistant prostate cancer resistance to enzalutamide and metastasis via miR-5089-5p/SPINK1/ MAPK/MMP9 signaling
por: Wang, Zhi-Chao, et al.
Publicado: (2020)

miR-133b suppresses metastasis by targeting HOXA9 in human colorectal cancer
por: Wang, Xiao, et al.
Publicado: (2017)

MicroRNA miR-328 Regulates Zonation Morphogenesis by Targeting CD44 Expression
por: Wang, Chia-Hui, et al.
Publicado: (2008)

A switch from CD44(+) cell to EMT cell drives the metastasis of prostate cancer
por: Shang, Zhiqun, et al.
Publicado: (2014)

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition
por: Zhang, Xiaoguang, et al.
Publicado: (2016)

MiR-33a suppresses breast cancer cell proliferation and metastasis by targeting ADAM9 and ROS1
por: Zhang, Chuankai, et al.
Publicado: (2015)

miR-582-3p and miR-582-5p Suppress Prostate Cancer Metastasis to Bone by Repressing TGF-β Signaling
por: Huang, Shuai, et al.
Publicado: (2019)

miR-26a Suppresses Tumor Growth and Metastasis by Targeting FGF9 in Gastric Cancer
por: Deng, Min, et al.
Publicado: (2013)

The role of NUMB/NUMB isoforms in cancer stem cells
por: Choi, Hye Yeon, et al.
Publicado: (2021)

MiR-520b as a novel molecular target for suppressing stemness phenotype of head-neck cancer by inhibiting CD44
por: Lu, Ya-Ching, et al.
Publicado: (2017)

miR-181 suppresses metastasis via MMP-14
por: Roth, Eric, et al.
Publicado: (2015)

miR-124 represses the mesenchymal features and suppresses metastasis in Ewing sarcoma
por: Li, Yunyun, et al.
Publicado: (2016)

SIRT2, a direct target of miR‐212‐5p, suppresses the proliferation and metastasis of colorectal cancer cells
por: Du, Feng, et al.
Publicado: (2020)

miR-31-NUMB Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells
por: Chou, Chung-Hsien, et al.
Publicado: (2021)

Suppression of ANT2 by miR-137 Inhibits Prostate Tumorigenesis
por: Zhang, Heyuan, et al.
Publicado: (2021)

Extracellular HMGB1 promotes CD44 expression in hepatocellular carcinoma via regulating miR-21
por: Li, Jun, et al.
Publicado: (2021)

MiR-429 suppresses the progression and metastasis of osteosarcoma by targeting ZEB1
por: Deng, Yi, et al.
Publicado: (2017)

miR-9 Acts as an OncomiR in Prostate Cancer through Multiple Pathways That Drive Tumour Progression and Metastasis
por: Seashols-Williams, S. J., et al.
Publicado: (2016)

ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis
por: Chiu, Kuo-Liang, et al.
Publicado: (2015)

miR-146a Enhances the Oncogenicity of Oral Carcinoma by Concomitant Targeting of the IRAK1, TRAF6 and NUMB Genes
por: Hung, Pei-Shi, et al.
Publicado: (2013)

Palmitic acid promotes human retinal pigment epithelial cells migration by upregulating miR-222 expression and inhibiting NUMB
por: Li, Fengzhi, et al.
Publicado: (2023)

Inhibition of miR-9-5p suppresses prostate cancer progress by targeting StarD13
por: Chen, Lin, et al.
Publicado: (2019)

Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model
por: Banyard, Jacqueline, et al.
Publicado: (2013)

miR-143 and miR-145 inhibit gastric cancer cell migration and metastasis by suppressing MYO6
por: Lei, Chao, et al.
Publicado: (2017)

miR186 suppresses prostate cancer progression by targeting Twist1
por: Zhao, Xian, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ck1vhlvq46drsse0av7nrlbtr8