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Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia

Neonatal hyperbilirubinemia or jaundice is associated with kernicterus, resulting in permanent neurological damage or even death. Conventional phototherapy does not prevent hyperbilirubinemia or eliminate the need for exchange transfusion. Here we investigated the potential of therapeutic bile acids...

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Detalles Bibliográficos
Autores principales: van der Schoor, Lori W. E., Verkade, Henkjan J., Bertolini, Anna, de Wit, Sanne, Mennillo, Elvira, Rettenmeier, Eva, Weber, André A., Havinga, Rick, Valášková, Petra, Jašprová, Jana, Struik, Dicky, Bloks, Vincent W., Chen, Shujuan, Schreuder, Andrea B., Vítek, Libor, Tukey, Robert H., Jonker, Johan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160219/
https://www.ncbi.nlm.nih.gov/pubmed/34045606
http://dx.doi.org/10.1038/s41598-021-90687-5