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Translational Block in Stroke: A Constructive and “Out-of-the-Box” Reappraisal

Why can we still not translate preclinical research to clinical treatments for acute strokes? Despite > 1000 successful preclinical studies, drugs, and concepts for acute stroke, only two have reached clinical translation. This is the translational block. Yet, we continue to routinely model strok...

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Detalles Bibliográficos
Autores principales: Lourbopoulos, Athanasios, Mourouzis, Iordanis, Xinaris, Christodoulos, Zerva, Nefeli, Filippakis, Konstantinos, Pavlopoulos, Angelos, Pantos, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160233/
https://www.ncbi.nlm.nih.gov/pubmed/34054413
http://dx.doi.org/10.3389/fnins.2021.652403