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Multilayer modelling of the human transcriptome and biological mechanisms of complex diseases and traits

Here, we performed a comprehensive intra-tissue and inter-tissue multilayer network analysis of the human transcriptome. We generated an atlas of communities in gene co-expression networks in 49 tissues (GTEx v8), evaluated their tissue specificity, and investigated their methodological implications...

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Detalles Bibliográficos
Autores principales: Azevedo, Tiago, Dimitri, Giovanna Maria, Lió, Pietro, Gamazon, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160250/
https://www.ncbi.nlm.nih.gov/pubmed/34045472
http://dx.doi.org/10.1038/s41540-021-00186-6