White-tailed deer S96 prion protein does not support stable in vitro propagation of most common CWD strains

PrP(C) variation at residue 96 (G/S) plays an important role in the epidemiology of chronic wasting disease (CWD) in exposed white-tailed deer populations. In vivo studies have demonstrated the protective effect of serine at codon 96, which hinders the propagation of common CWD strains when expresse...

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Detalles Bibliográficos
Autores principales: Otero, Alicia, Duque Velásquez, Camilo, Aiken, Judd, McKenzie, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160261/
https://www.ncbi.nlm.nih.gov/pubmed/34045540
http://dx.doi.org/10.1038/s41598-021-90606-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160261/
https://www.ncbi.nlm.nih.gov/pubmed/34045540
http://dx.doi.org/10.1038/s41598-021-90606-8

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