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FORTIS: a live-cell assay to monitor AMPA receptors using pH-sensitive fluorescence tags

The real-time live fluorescent monitoring of surface AMPA receptors (AMPARs) could open new opportunities for drug discovery and phenotypic screening concerning neuropsychiatric disorders. We have developed FORTIS, a tool based on pH sensitivity capable of detecting subtle changes in surface AMPARs...

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Detalles Bibliográficos
Autores principales: Calleja-Felipe, María, Wojtas, Magdalena Natalia, Diaz-González, Marta, Ciceri, Dalila, Escribano, Raúl, Ouro, Alberto, Morales, Miguel, Knafo, Shira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160262/
https://www.ncbi.nlm.nih.gov/pubmed/34045447
http://dx.doi.org/10.1038/s41398-021-01457-w