MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer

Many immune suppressive mechanisms utilized by triple negative breast cancer (TNBC) are regulated by oncogenic epithelial-to-mesenchymal transition (EMT). How TNBC EMT impacts innate immune cells is not fully understood. To determine how TNBC suppresses antitumor macrophages, we used microRNA-200c (...

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Detalles Bibliográficos
Autores principales: Williams, Michelle M., Christenson, Jessica L., O’Neill, Kathleen I., Hafeez, Sabrina A., Ihle, Claire L., Spoelstra, Nicole S., Slansky, Jill E., Richer, Jennifer K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160264/
https://www.ncbi.nlm.nih.gov/pubmed/34045467
http://dx.doi.org/10.1038/s41523-021-00273-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160264/
https://www.ncbi.nlm.nih.gov/pubmed/34045467
http://dx.doi.org/10.1038/s41523-021-00273-1

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