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MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
Many immune suppressive mechanisms utilized by triple negative breast cancer (TNBC) are regulated by oncogenic epithelial-to-mesenchymal transition (EMT). How TNBC EMT impacts innate immune cells is not fully understood. To determine how TNBC suppresses antitumor macrophages, we used microRNA-200c (...
Autores principales: | Williams, Michelle M., Christenson, Jessica L., O’Neill, Kathleen I., Hafeez, Sabrina A., Ihle, Claire L., Spoelstra, Nicole S., Slansky, Jill E., Richer, Jennifer K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160264/ https://www.ncbi.nlm.nih.gov/pubmed/34045467 http://dx.doi.org/10.1038/s41523-021-00273-1 |
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