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Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis

Long-term infection of the airways of cystic fibrosis patients with Pseudomonas aeruginosa is often accompanied by a reduction in bacterial growth rate. This reduction has been hypothesised to increase within-patient fitness and overall persistence of the pathogen. Here, we apply adaptive laboratory...

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Detalles Bibliográficos
Autores principales: La Rosa, Ruggero, Rossi, Elio, Feist, Adam M., Johansen, Helle Krogh, Molin, Søren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160344/
https://www.ncbi.nlm.nih.gov/pubmed/34045458
http://dx.doi.org/10.1038/s41467-021-23451-y