Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

In a randomized clinical trial of 86 hospitalized COVID-19 patients comparing standard care to treatment with 300mL convalescent plasma containing high titers of neutralizing SARS-CoV-2 antibodies, no overall clinical benefit was observed. Using a comprehensive translational approach, we unravel the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gharbharan, Arvind, Jordans, Carlijn C. E., GeurtsvanKessel, Corine, den Hollander, Jan G., Karim, Faiz, Mollema, Femke P. N., Stalenhoef – Schukken, Janneke E., Dofferhoff, Anthonius, Ludwig, Inge, Koster, Adrianus, Hassing, Robert-Jan, Bos, Jeannet C., van Pottelberge, Geert R., Vlasveld, Imro N., Ammerlaan, Heidi S. M., van Leeuwen – Segarceanu, Elena M., Miedema, Jelle, van der Eerden, Menno, Schrama, Thijs J., Papageorgiou, Grigorios, te Boekhorst, Peter, Swaneveld, Francis H., Mueller, Yvonne M., Schreurs, Marco W. J., van Kampen, Jeroen J. A., Rockx, Barry, Okba, Nisreen M. A., Katsikis, Peter D., Koopmans, Marion P. G., Haagmans, Bart L., Rokx, Casper, Rijnders, Bart J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160346/
https://www.ncbi.nlm.nih.gov/pubmed/34045486
http://dx.doi.org/10.1038/s41467-021-23469-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160346/
https://www.ncbi.nlm.nih.gov/pubmed/34045486
http://dx.doi.org/10.1038/s41467-021-23469-2

Ejemplares similares