Viral fibrotic scoring and drug screen based on MAPK activity uncovers EGFR as a key regulator of COVID-19 fibrosis

Understanding the molecular basis of fibrosis, the lethal complication of COVID-19, is urgent. By the analysis of RNA-sequencing data of SARS-CoV-2-infected cells combined with data mining we identified genes involved in COVID-19 progression. To characterize their implication in the fibrosis develop...

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Detalles Bibliográficos
Autores principales: Vagapova, Elmira R., Lebedev, Timofey D., Prassolov, Vladimir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160348/
https://www.ncbi.nlm.nih.gov/pubmed/34045585
http://dx.doi.org/10.1038/s41598-021-90701-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160348/
https://www.ncbi.nlm.nih.gov/pubmed/34045585
http://dx.doi.org/10.1038/s41598-021-90701-w

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