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Comparison of the major cell populations among osteoarthritis, Kashin–Beck disease and healthy chondrocytes by single-cell RNA-seq analysis

Chondrocytes are the key target cells of the cartilage degeneration that occurs in Kashin–Beck disease (KBD) and osteoarthritis (OA). However, the heterogeneity of articular cartilage cell types present in KBD and OA patients and healthy controls is still unknown, which has prevented the study of th...

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Detalles Bibliográficos
Autores principales: Wang, Xi, Ning, Yujie, Zhang, Pan, Poulet, Blandine, Huang, Ruitian, Gong, Yi, Hu, Minhan, Li, Cheng, Zhou, Rong, Lammi, Mikko J., Guo, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160352/
https://www.ncbi.nlm.nih.gov/pubmed/34045450
http://dx.doi.org/10.1038/s41419-021-03832-3