Human stem cells harboring a suicide gene improve the safety and standardisation of neural transplants in Parkinsonian rats

Despite advancements in human pluripotent stem cells (hPSCs) differentiation protocols to generate appropriate neuronal progenitors suitable for transplantation in Parkinson’s disease, resultant grafts contain low proportions of dopamine neurons. Added to this is the tumorigenic risk associated with...

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Detalles Bibliográficos
Autores principales: de Luzy, Isabelle R., Law, Kevin C. L., Moriarty, Niamh, Hunt, Cameron P. J., Durnall, Jennifer C., Thompson, Lachlan H., Nagy, Andras, Parish, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160354/
https://www.ncbi.nlm.nih.gov/pubmed/34045451
http://dx.doi.org/10.1038/s41467-021-23125-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160354/
https://www.ncbi.nlm.nih.gov/pubmed/34045451
http://dx.doi.org/10.1038/s41467-021-23125-9

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