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A Novel CAR Expressing NK Cell Targeting CD25 With the Prospect of Overcoming Immune Escape Mechanism in Cancers

For many years, high-affinity subunit of IL-2 receptor (CD25) has been considered as a promising therapeutic target for different pathologic conditions like allograft rejection, autoimmunity, and cancers. Although CD25 is transiently expressed by newly-activated T cells, it is the hallmark of regula...

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Detalles Bibliográficos
Autores principales: Dehbashi, Moein, Hojati, Zohreh, Motovali-bashi, Majid, Ganjalikhany, Mohamad Reza, Cho, William C., Shimosaka, Akihiro, Navabi, Parnian, Ganjalikhani-Hakemi, Mazdak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160382/
https://www.ncbi.nlm.nih.gov/pubmed/34055618
http://dx.doi.org/10.3389/fonc.2021.649710