Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

Decreased human epididymis protein 4 (HE4) plasma levels were reported in cystic fibrosis (CF) patients under CFTR potentiator ivacaftor therapy, which inversely correlated with lung function improvement. In this study, we investigated whether HE4 expression was affected via modulation of CFTR funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Bene, Zsolt, Fejes, Zsolt, Szanto, Tibor Gabor, Fenyvesi, Ferenc, Váradi, Judit, Clarke, Luka A., Panyi, Gyorgy, Macek, Milan, Amaral, Margarida D., Balogh, István, Nagy, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160512/
https://www.ncbi.nlm.nih.gov/pubmed/34054511
http://dx.doi.org/10.3389/fphar.2021.592184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160512/
https://www.ncbi.nlm.nih.gov/pubmed/34054511
http://dx.doi.org/10.3389/fphar.2021.592184

Ejemplares similares