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Response Rate and Survival at Key Timepoints With PD-1 Blockade vs Chemotherapy in PD-L1 Subgroups: Meta-Analysis of Metastatic NSCLC Trials

BACKGROUND: Expression of programmed cell death ligand 1 (PD-L1) on tumor cells with or without immune cells is widely reported in clinical trials of programmed cell death receptor 1 (PD-1) blockade in metastatic non-small cell lung cancer. Various cutpoints have been studied. METHODS: We performed...

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Detalles Bibliográficos
Autores principales: Man, Johnathan, Millican, Jared, Mulvey, Arthur, Gebski, Val, Hui, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160531/
https://www.ncbi.nlm.nih.gov/pubmed/34084999
http://dx.doi.org/10.1093/jncics/pkab012