Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance

A variety of antiviral treatments for COVID-19 have been investigated, involving many repurposed drugs. Currently, the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp, encoded by nsp12-nsp7-nsp8) has been targeted by numerous inhibitors, e.g., remdesivir, the only provisionally approved treatment to-d...

Descripción completa

Detalles Bibliográficos
Autores principales: Mari, Alfredo, Roloff, Tim, Stange, Madlen, Søgaard, Kirstine K., Asllanaj, Erblin, Tauriello, Gerardo, Alexander, Leila Tamara, Schweitzer, Michael, Leuzinger, Karoline, Gensch, Alexander, Martinez, Aurélien E., Bielicki, Julia, Pargger, Hans, Siegemund, Martin, Nickel, Christian H., Bingisser, Roland, Osthoff, Michael, Bassetti, Stefano, Sendi, Parham, Battegay, Manuel, Marzolini, Catia, Seth-Smith, Helena M. B., Schwede, Torsten, Hirsch, Hans H., Egli, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160703/
https://www.ncbi.nlm.nih.gov/pubmed/34069681
http://dx.doi.org/10.3390/microorganisms9051094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160703/
https://www.ncbi.nlm.nih.gov/pubmed/34069681
http://dx.doi.org/10.3390/microorganisms9051094

Ejemplares similares