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Potent Antimicrobial and Antibiofilm Activities of Feleucin-K3 Analogs Modified by α-(4-Pentenyl)-Ala against Multidrug-Resistant Bacteria

The dramatic increase in antimicrobial resistance (AMR) highlights an urgent need to develop new antimicrobial therapies. Thus, antimicrobial peptides (AMPs) have emerged as promising novel antibiotic alternatives. Feleucin-K3 is an amphiphilic α-helical nonapeptide that has powerful antimicrobial a...

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Detalles Bibliográficos
Autores principales: Guo, Xiaomin, Yan, Tiantian, Rao, Jing, Yue, Xin, Pei, Xiong, Deng, Jiahui, Sun, Wangsheng, Yang, Wenle, Zhang, Bangzhi, Xie, Junqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160793/
https://www.ncbi.nlm.nih.gov/pubmed/34069651
http://dx.doi.org/10.3390/biom11050761