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Inactivating Mutations of the IK Gene Weaken Ku80/Ku70-Mediated DNA Repair and Sensitize Endometrial Cancer to Chemotherapy

SIMPLE SUMMARY: Some endometrial cancer (EC) patients have different prognoses and responses to treatment, even among those with the same stage and tumor grade as assessed by the International Federation of Gynecology and Obstetrics (FIGO) criteria. Molecular classification may make up for this defi...

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Detalles Bibliográficos
Autores principales: Gao, Chao, Jin, Guangxu, Forbes, Elizabeth, Mangala, Lingegowda S., Wang, Yingmei, Rodriguez-Aguayo, Cristian, Amero, Paola, Bayraktar, Emine, Yan, Ye, Lopez-Berestein, Gabriel, Broaddus, Russell R., Sood, Anil K., Xue, Fengxia, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160817/
https://www.ncbi.nlm.nih.gov/pubmed/34065218
http://dx.doi.org/10.3390/cancers13102487