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Inactivating Mutations of the IK Gene Weaken Ku80/Ku70-Mediated DNA Repair and Sensitize Endometrial Cancer to Chemotherapy
SIMPLE SUMMARY: Some endometrial cancer (EC) patients have different prognoses and responses to treatment, even among those with the same stage and tumor grade as assessed by the International Federation of Gynecology and Obstetrics (FIGO) criteria. Molecular classification may make up for this defi...
Autores principales: | Gao, Chao, Jin, Guangxu, Forbes, Elizabeth, Mangala, Lingegowda S., Wang, Yingmei, Rodriguez-Aguayo, Cristian, Amero, Paola, Bayraktar, Emine, Yan, Ye, Lopez-Berestein, Gabriel, Broaddus, Russell R., Sood, Anil K., Xue, Fengxia, Zhang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160817/ https://www.ncbi.nlm.nih.gov/pubmed/34065218 http://dx.doi.org/10.3390/cancers13102487 |
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