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Effect of Sodium Valproate on the Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin

Rhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis pigmentosa. Several therapeutic strategies have attempted to address and counteract...

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Detalles Bibliográficos
Autores principales: Razzaghi, Neda, Fernandez-Gonzalez, Pol, Mas-Sanchez, Aina, Vila-Julià, Guillem, Perez, Juan Jesus, Garriga, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160834/
https://www.ncbi.nlm.nih.gov/pubmed/34069614
http://dx.doi.org/10.3390/molecules26103032