Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication

Human cytomegalovirus (HCMV) is a leading cause of severe diseases in immunocompromised individuals, including AIDS patients and transplant recipients, and in congenitally infected newborns. The utility of available drugs is limited by poor bioavailability, toxicity, and emergence of resistant strai...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghassabian, Hanieh, Falchi, Federico, Timmoneri, Martina, Mercorelli, Beatrice, Loregian, Arianna, Palù, Giorgio, Alvisi, Gualtiero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160850/
https://www.ncbi.nlm.nih.gov/pubmed/34065234
http://dx.doi.org/10.3390/v13050941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160850/
https://www.ncbi.nlm.nih.gov/pubmed/34065234
http://dx.doi.org/10.3390/v13050941

Ejemplares similares