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Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication
Human cytomegalovirus (HCMV) is a leading cause of severe diseases in immunocompromised individuals, including AIDS patients and transplant recipients, and in congenitally infected newborns. The utility of available drugs is limited by poor bioavailability, toxicity, and emergence of resistant strai...
Autores principales: | Ghassabian, Hanieh, Falchi, Federico, Timmoneri, Martina, Mercorelli, Beatrice, Loregian, Arianna, Palù, Giorgio, Alvisi, Gualtiero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160850/ https://www.ncbi.nlm.nih.gov/pubmed/34065234 http://dx.doi.org/10.3390/v13050941 |
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