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Discoidin Domain Receptor 2 Mediates Lysophosphatidic Acid-Induced Ovarian Cancer Aggressiveness

Lysophosphatidic acid (LPA), a bioactive lipid produced extracellularly by autotaxin (ATX), has been known to induce various pathophysiological events, including cancer cell invasion and metastasis. Discoidin domain receptor 2 (DDR2) expression is upregulated in ovarian cancer tissues, and is closel...

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Detalles Bibliográficos
Autores principales: Jeong, Bo Young, Cho, Kyung Hwa, Yoon, Se-Hee, Park, Chang Gyo, Park, Hwan-Woo, Lee, Hoi Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160857/
https://www.ncbi.nlm.nih.gov/pubmed/34065317
http://dx.doi.org/10.3390/ijms22105374