Changes in Lactate Production, Lactate Dehydrogenase Genes Expression and DNA Methylation in Response to Tamoxifen Resistance Development in MCF-7 Cell Line

Lactate dehydrogenase (LDH) is a key enzyme in the last step of glycolysis, playing a role in the pyruvate-to-lactate reaction. It is associated with the prognosis and metastasis of many cancers, including breast cancer. In this study, we investigated the changes in LDH gene expression and lactate c...

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Detalles Bibliográficos
Autores principales: Hamadneh, Lama, Al-Lakkis, Lara, Alhusban, Ala A., Tarawneh, Shahd, Abu-Irmaileh, Bashaer, Albustanji, Sokiyna, Al-Bawab, Abdel Qader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160872/
https://www.ncbi.nlm.nih.gov/pubmed/34069745
http://dx.doi.org/10.3390/genes12050777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160872/
https://www.ncbi.nlm.nih.gov/pubmed/34069745
http://dx.doi.org/10.3390/genes12050777

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