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The Insulin Receptor: A Potential Target of Amarogentin Isolated from Gentiana rigescens Franch That Induces Neurogenesis in PC12 Cells

Amarogentin (AMA) is a secoiridoid glycoside isolated from the traditional Chinese medicine, Gentiana rigescens Franch. AMA exhibits nerve growth factor (NGF)-mimicking and NGF-enhancing activities in PC12 cells and in primary cortical neuron cells. In this study, a possible mechanism was found show...

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Detalles Bibliográficos
Autores principales: Cheng, Lihong, Osada, Hiroyuki, Xing, Tianyan, Yoshida, Minoru, Xiang, Lan, Qi, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160887/
https://www.ncbi.nlm.nih.gov/pubmed/34065446
http://dx.doi.org/10.3390/biomedicines9050581