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The Insulin Receptor: A Potential Target of Amarogentin Isolated from Gentiana rigescens Franch That Induces Neurogenesis in PC12 Cells
Amarogentin (AMA) is a secoiridoid glycoside isolated from the traditional Chinese medicine, Gentiana rigescens Franch. AMA exhibits nerve growth factor (NGF)-mimicking and NGF-enhancing activities in PC12 cells and in primary cortical neuron cells. In this study, a possible mechanism was found show...
Autores principales: | Cheng, Lihong, Osada, Hiroyuki, Xing, Tianyan, Yoshida, Minoru, Xiang, Lan, Qi, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160887/ https://www.ncbi.nlm.nih.gov/pubmed/34065446 http://dx.doi.org/10.3390/biomedicines9050581 |
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